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Updated: Jan 16, 2026

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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微生物群によって誘発されたT細胞の可塑性は,免疫媒介による腫瘍制御を可能にします.

Tariq A Najar1, Yuan Hao2,3, Yuhan Hao4,5

  • 1Department of Cell Biology, New York University School of Medicine, New York, NY, USA.

Nature
|January 14, 2026
PubMed
まとめ

セグメンテッド・フィラメント菌 (SFB) のコロニー化は,Tヘルパー17 (TH17) 細胞を教育することによって,プログラム細胞死タンパク質1 (PD-1) 治療の有効性を高めます. これらの腸で形成された細胞はTヘルパー1 (TH1) のような細胞になり,抗腫瘍免疫とCD8+T細胞の反応を高めます.

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