急性ストレスは前頭前野の活性化とfNIRSベースの超スキャンからの証拠に基づく実行・社会的機能に影響を与える
Zhihua Guo1, Yue Gong1, Liu Yang2
1Department of Military Medical Psychology, The Fourth Military Medical University, Xi'an, China.
Brain and behavior
|January 16, 2026
まとめ
急性ストレスはワーキングメモリ学習を悪化させたが、他の実行機能と協調性は維持した。ストレスは前頭前野の活性化と脳間同期を増加させ、実行機能と社会的機能をつなぐ代償メカニズムの可能性を示唆した。
科学分野:
- 神経科学
- 認知心理学
- 社会神経科学
背景:
- 急性ストレスは実行機能と社会的行動に一貫性のない影響を与え、その神経メカニズムは十分に理解されていない。
- 急性ストレス、実行機能、二者協力の関係を調査することは、これらの複雑な相互作用を理解するために不可欠である。
主な方法:
- 健康な男性学部生86名を対象に、Trier Social Stress Test for Groups(TSST-G)またはプラセボ対照を実施した。
- 参加者は介入前後に実行機能課題(3バック、Go/Nogo、Stroop、課題切り替え)および協力課題を完了した。
- 機能的近赤外分光法(fNIRS)を用いて前頭前野(PFC)の活性化と脳間同期(IBS)を測定した。
結論:
- 急性ストレスはワーキングメモリ学習を妨げたが、反応抑制、干渉制御、認知柔軟性、協力行動は維持された。
- ストレス下での神経活性化とIBSの増加は、実行機能と社会的機能をつなぐ代償メカニズムを示唆する可能性がある。
- 本研究結果は、「実行・社会的機能カップリング仮説」を支持し、ストレスと社会的行動に関する将来の研究のためのヒューリスティックモデルを提供する。
さらに関連する動画
関連する概念動画
Introduction to Stress and Lifestyle
517
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
517
Psychological Responses to Stress
485
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
485
Physiological Foundation of Stress
580
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
Role of the Sympathetic Nervous System
Adrenaline triggers the...
580
Components of Stress
504
Stress analysis under multiple loading conditions is intricate, necessitating a comprehensive grasp of normal and shearing stresses. Consider a small cube at point O, subjected to stress on all six faces, visible or not. Normal stress components σx, σy, σz act perpendicularly to the x, y, and z axes. Shearing stress components τxy and τxz are exerted on faces perpendicular to these axes.
Interestingly, the hidden cube faces also experience these stresses, equal and...
Interestingly, the hidden cube faces also experience these stresses, equal and...
504
Hypothalamic-Pituitary Axis
65.5K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
65.5K


