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Updated: Jan 18, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
急性膵炎:ナラティブレビュー
1Internal Medicine, Gastroenterology and Hepatology, School of Medicine and Dentistry, The University of Dodoma, Dodoma, TZA.
Abstract:
Acute pancreatitis is an increasingly prevalent gastrointestinal condition worldwide with substantial morbidity and mortality. This narrative review summarises the epidemiology and contemporary management of acute pancreatitis. A literature search was conducted in May 2025 to identify studies published from inception to May 2025 in MEDLINE/PubMed, Web of Science, and Scopus. Electronic searches were supplemented by manual screening of reference lists from key articles identified via Google Scholar using the following key terms: "acute pancreatitis, prevalence, epidemiology, aetiology and management" For PubMed, the Medical Subject Headings (MeSH) terms were used based on the research question. Boolean operators were employed to fine-tune the search terms. There were no language restrictions. The diagnostic criteria for acute pancreatitis were aligned with the American College of Gastroenterology guidelines for the management of acute pancreatitis. After screening abstracts and full texts, 31 articles were included in this review. Acute pancreatitis is still a major health concern, with the burden increasing globally, mainly attributed to the increased burden of obesity and gallstones. The most common etiologies of acute pancreatitis are ascribed to biliary disease, alcohol consumption and hypertriglyceridemia. Acute pancreatitis is associated with substantial morbidity and mortality in its severe form, underscoring the need for timely diagnosis and appropriate management to improve outcomes.
さらに関連する動画
07:10Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
Published on: April 1, 2022
07:38Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
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関連する概念動画
Acute Pancreatitis II: Clinical Manifestations and Management
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Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Acute Pyelonephritis I: Introduction
Acute Kidney Injury I: Introduction