関連する実験動画

Updated: Jan 20, 2026

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential
07:41

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential

Published on: January 18, 2019

8.1K

テニポシドによるSTING活性化：cGAS刺激を超えた直接的なメカニズムの可能性

Javier Arranz-Herrero1,2,3, Laura Marquez-Cantudo4, Sergio Rius-Rocabert1,3

  • 1Microbiology Section, Departamento de Ciencias, Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.

Frontiers in immunology
|January 19, 2026
PubMed
まとめ

抗がん剤であるテニポシドは、STIMulator of Interferon Genes（STING）タンパク質に直接結合して活性化します。この発見は、自然免疫刺激の新たなメカニズムを明らかにし、テニポシドの治療的免疫調節への転用を示唆しています。

キーワード:
サイクリックジヌクレオチド（CDNs）ハイスループット仮想スクリーニング（HTVS）IFN-β免疫療法薬の転用等温滴定カロリメトリー（ITC）分子ドッキングSTINGテニポシド

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Hair type commonly seen in historically underrepresented minorities appears to interfere with transcranial magnetic stimulation (TMS). Here we describe a hair braiding method (The Sol Braiding Technique) that improves...
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