メタゲノム次世代シーケンシングによるレンニエール症候群の迅速診断:症例報告
1Department of Emergency, the 960th Hospital of the People's Liberation Army, Shandong Second Medical University (The 960th Hospital of the PLA Joint Logistics Support Force), Jinan, Shandong, China.
Abstract:
Lemierre's syndrome, also known as postopharyngeal septicaemia or necrobacillosis, is a rare, fatal opportunistic infection, often caused by Fusobacterium necrophorum invading the throat. Bacterial culture is a conventional method to establish a diagnosis, but is time-consuming and insensitive in some cases. Metagenomic next-generation sequencing (mNGS), as an emerging technique, has become an important supplementary detection method for infectious diseases. It greatly favors the rapid, precise diagnosis and treatment of Lemierre's syndrome through accurately obtaining etiological information. We reported a case of Lemierre's syndrome that was rapidly and accurately diagnosed by mNGS.


