関連する実験動画

Updated: Jan 20, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Published on: January 25, 2016

甲状腺刺激ホルモン（TSH）を突発性難聴の聴覚予後因子として評価する

Sang Hoon Kim¹, Hanyuk Lee¹, Mi Ra Kim¹

¹Department of Otorhinolaryngology-Head and Neck Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.

Acta oto-laryngologica

|January 19, 2026

まとめ

甲状腺刺激ホルモン（TSH）レベルは、甲状腺機能低下症を伴う突発性難聴（SSNHL）患者の聴覚回復と相関する。TSHレベルが高いほど聴覚予後は不良であり、SSNHL治療の潜在的な予後因子として示唆される。

科学分野:

耳鼻咽喉科学
内分泌学
聴覚学

背景:

甲状腺機能障害は突発性難聴（SSNHL）と関連している。
甲状腺刺激ホルモン（TSH）は甲状腺機能の重要な指標である。

研究の目的:

甲状腺機能低下症患者における突発性難聴（SSNHL）治療成績に対するTSHレベルの影響を評価する。
TSHがSSNHL回復の予後マーカーとして機能するかどうかを判断する。

主な方法:

SSNHLを伴う甲状腺機能低下症患者41名を対象とした後向きカルテレビュー。
Siegelの基準に基づいて回復群と非回復群に患者を分類。
聴力ゲインとTSHレベルの分析。

主要な成果:

最終的な聴力ゲインとTSHレベルの間には有意な負の相関が観察された。回復群と比較して、非回復群の患者は有意に高いTSHレベルを示した。

結論:

SSNHL患者において、TSHレベルは聴力ゲインと負の相関がある。
TSHの上昇はSSNHLの治療成績不良を予測する可能性がある。
TSHは甲状腺機能低下症患者のSSNHL管理において有用な予後因子となり得る。

キーワード:

TSH 聴覚予後突発性難聴

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