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Updated: Jan 21, 2026

Author Spotlight: Optimizing Hollow-Fiber Membranes for Continuous Liquid-Liquid Extraction of Medium-Chain Fatty Acids

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Published on: August 9, 2024

Broussonetia papyrifera（コウゾ）葉抽出発酵液の抗黒化および抗酸化活性

Bo Dou¹, Rui-Qi Wu¹, Xiao-Lai Ma¹

¹School of Pharmacy, Guilin Medical University, Guilin 541199, China.

Journal of Asian natural products research

|January 19, 2026

Abstract:

Broussonetia papyrifera leaves are a medicinal plant rich in bioactive substances. This study utilized microbial fermentation of B. papyrifera leaf extract (BLE) to screen out Lactobacillus rhamnosus and Bifidobacterium papyrifera as the most suitable fermentation strains. The total phenols, total flavonoids, total tannins and total triterpenoids content increased after fermentation. The fermentation broth of L. rhamnosus and BLE (BLFs) could inhibit the tyrosinase, melanin production and related protein expression of mouse melanoma cell B16-F10. The fermentation broth of B. bifidum and BLE (BBFs) exhibited significant antioxidant effects. It indicates that the fermented BLE has great application potential in the fields of medicine, cosmetics and related areas.

キーワード:

コウゾ葉発酵液抗酸化活性プロバイオティクス発酵チロシナーゼ阻害

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A Gnotobiotic System for Studying Microbiome Assembly in the Phyllosphere and in Vegetable Fermentation

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