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関連する概念動画

Criticisms of the Evolutionary Perspective01:23

Criticisms of the Evolutionary Perspective

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In a study where individuals posing as strangers offered compliments and proposed casual sex to students, the responses differed significantly based on gender. Not a single woman accepted the proposal, while 70% of the men agreed. This outcome provides a useful scenario to explore through the lens of evolutionary psychology and social learning theory, highlighting the diverse perspectives on human sexual behaviors.
Evolutionary psychology provides one explanation for these findings, suggesting...
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Classification of Skeletal Muscle Fibers01:48

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Skeletal muscles continuously produce ATP to provide the energy that enables muscle contractions. Skeletal muscle fibers can be categorized into three types based on differences in their contraction speed and how they produce ATP, as well as physical differences related to these factors. Most human muscles contain all three muscle fiber types, albeit in varying proportions.
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...
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Relaxation of Skeletal Muscles01:29

Relaxation of Skeletal Muscles

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The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
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Overview of Skeletal Muscle01:15

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Skeletal muscles are composed of a bundle of muscle fibers and are attached to bones through tendons. Each skeletal muscle fiber is a single muscle cell. The sarcolemma, the plasma membrane of a skeletal muscle cell, consists of a lipid bilayer and glycocalyx that supports muscle fibers. The sarcolemma extends into the muscle cells to form tubular structures called transverse or T-tubules. Each side of the T-tubules consists of a membrane-bound structure called the sarcoplasmic reticulum,...
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Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.
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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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関連する実験動画

Updated: Jan 21, 2026

Manual Muscle Testing: A Method of Measuring Extremity Muscle Strength Applied to Critically Ill Patients
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骨格筋量の測定法に関する基準法:批判的考察

Steven B Heymsfield1, Houchun H Hu2, Edvin Johanssen3

  • 1Pennington Biomedical Research Center, LSU System, Baton Rouge, Louisiana, USA.

Journal of cachexia, sarcopenia and muscle
|January 20, 2026
PubMed
まとめ
この要約は機械生成です。

ヒトの骨格筋(SM)量を測定するための単一のゴールドスタンダードは存在しない。本レビューは、正確なSM定量化のための生体測定法の標準化されたプロトコルと正確な用語の必要性を強調する。

キーワード:
生体組成悪液質フレイル栄養失調栄養評価肥満サルコペニア

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科学分野:

  • 生理学
  • 生物医学工学
  • 医用画像処理

背景:

  • 骨格筋(SM)は、健康と疾患において重要な役割を果たしている。
  • ヒトのSM量の定量化は、普遍的に受け入れられているゴールドスタンダード法を欠いている。
  • 現在の法は、invitro法とinvivo法に大別される。

研究 の 目的:

  • ヒトの骨格筋量と組成を定量化するための既存のinvivo法の批判的レビュー。
  • 現在の基準法の限界とその誘導技術への影響の特定。
  • SM測定の精度、再現性、および明確性を向上させるための推奨事項の提案。

主な方法:

  • 骨格筋定量化のためのinvitro法およびinvivo法の系統的レビュー。
  • invivo法を基準法(上位)および二次法(下位)に分類。
  • 基準法(CT、MRI、DXA)のプロトコル、用語、および検証手順の批判的分析。

主要な成果:

  • invitro法はほとんど報告されておらず、現在の臨床用途には適していない。
  • 3つのinvivo法(CT、MRI、DXA)は基準法と見なされているが、標準化されたプロトコルと用語が欠如している。
  • 下位の法は基準法に対する校正が必要であり、不正確さを伝播させる。
  • 基準法では、取得プロトコルと画像解析に大きなばらつきが存在する。

結論:

  • invivo骨格筋量定量化のための決定的なゴールドスタンダードは存在しない。
  • SM測定におけるCT、MRI、およびDXAには、標準化されたプロトコルと正確な用語が不可欠である。
  • 筋肉量と組成分析のための最適なガイドラインを確立するには、将来の専門家コンセンサスが必要である。