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Updated: Jan 22, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
小児および青年期のがん・血液疾患患者におけるデング熱:症例シリーズ
María A Rodríguez1, María B Leone1, Micaela Muras1
1Hospital de Niños Pedro de Elizalde, Autonomous City of Buenos Aires, Argentina.
Abstract:
Dengue is a viral disease transmitted mainly by the Aedes aegypti mosquito. Argentina has seen a significant increase in epidemics in recent years. Pediatric patients with oncohematological diseases are particularly vulnerable due to their immunosuppression, which can predispose them to severe cases. This report presents five clinical cases of pediatric patients with oncohematological diseases who developed dengue infection, illustrating the variability in its clinical presentation. Symptoms were heterogeneous, ranging from mild forms to severe cases with liver failure, bleeding, and the need for intensive care. Early identification, close monitoring, and an interdisciplinary approach are key to management. This series of cases reinforces the need for active clinical surveillance for fever in an epidemiological context, even in the absence of typical symptoms.
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