生体弁大動脈弁血栓症による再発性下壁STEMIの1例
Thitikorn Kittiboonya1, Surakiat Leelasithorn2, Mann Chandavimol2
1Sukumvit Hospital, Bangkok, Thailand.
JACC. Case reports
|January 21, 2026
まとめ
弁置換後の血栓症によるSTEMIはまれである。本症例は、手術後15年を経て、冠動脈閉塞のない心筋梗塞(MINOCA)として現れた生体弁血栓症の診断の遅れを示す。
科学分野:
- 循環器内科
- 心臓血管外科
背景:
- 弁置換人工弁血栓症は、ST上昇型心筋梗塞(STEMI)のまれな原因である。
- 本症例は、弁置換人工弁血栓症の診断上の課題を提示する。
研究 の 目的:
- 弁置換人工弁血栓症のまれな症例を強調すること。
- 後期に発症する生体弁血栓症の診断上の課題と臨床的意義を強調すること。
主な方法:
- 生体弁および僧帽弁置換術の既往のある71歳男性が、再発性の下壁STEMIで来院した。
- 冠動脈造影検査により、冠動脈に閉塞のない心筋梗塞(MINOCA)が明らかになった。
- 経食道心エコー検査により、右冠動脈起始部の間欠的な閉塞を引き起こす弁置換人工弁上の可動性血栓が特定された。
主要な成果:
- 患者は、冠動脈の有意な狭窄がないにもかかわらず、再発性のSTEMIを呈した。
- 弁置換人工弁上に可動性血栓2cmを検出した。
- 血栓は右冠動脈起始部を間欠的に閉塞していた。
結論:
- 弁置換人工弁血栓症は、本症例のように、通常観察されるよりも大幅に遅れて発生する可能性がある(移植後15年)。
- 弁血栓症は、手術からの期間に関係なく、血栓塞栓性イベントまたはMINOCAを呈する弁置換人工弁を有する患者において考慮されるべきである。
- 弁置換人工弁血栓症の管理および合併症の予防には、特に経食道心エコー検査による包括的な画像診断による早期診断が不可欠である。
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