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Updated: Jan 23, 2026

Facile Synthesis of Worm-like Micelles by Visible Light Mediated Dispersion Polymerization Using Photoredox Catalyst

Facile Synthesis of Worm-like Micelles by Visible Light Mediated Dispersion Polymerization Using Photoredox Catalyst

Published on: June 8, 2016

可視光照射による2,3-ジ置換キナゾリン-4(3H)-オン合成のための3成分環化戦略

Yingying Wu¹, Lvyin Zheng¹, Yinyun Lin¹

¹Jiangxi Provincial Key Laboratory of Synthetic Pharmaceutical Chemistry, Gannan Normal University, Ganzhou 341000, China.

The Journal of organic chemistry

|January 21, 2026

Abstract:

We developed a visible-light-mediated, three-component annulation strategy for synthesizing 2,3-disubstituted quinazolin-4(3H)-ones from easily available starting materials under mild reaction conditions. Phenylthiourea intermediates, generated in situ from phenyl isothiocyanates and substituted anilines, undergo formal [4 + 2] annulation with isatins to afford the corresponding products. This process involves two C-N bond formations in a one-pot, two-step protocol. Crucially, the method requires no photocatalysts, transition metals, or external oxidants.

キーワード:

キナゾリン-4(3H)-オン可視光照射 3成分反応有機合成複素環化学

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