関連する実験動画
Updated: Jan 23, 2026

Oral Health Assessment by Lay Personnel for Older Adults
Published on: February 2, 2020
米国における違法薬物使用者間の口腔衛生格差:NHANES 2017-2018データを用いた二次分析
Purpose:
This study used data from the National Health and Nutrition Examination Survey (NHANES) to examine associations between the use of four illicit drugs (cocaine, heroin, marijuana, and methamphetamine) and the dental caries experience among adults in the US using the Decayed, Missing and Filled Teeth (DMFT) index.
Materials And Methods:
Data from NHANES 2017-2018, a cross-sectional study that included adults aged 18-69 years, was used in this study. A self-reported questionnaire was used to collect data related to drug use, and a calibrated dental examination was performed to diagnose caries. The associations among the illicit drug use, DMFT score, and score of each component were analyzed using zero-inflated negative binomial regression.
Results:
Marijuana was the most commonly used drug among the participants (60.9%). In adjusted zero-inflated negative binomial models, current heroin was associated with fewer missing teeth (IRR= 0.50, 95% CI: 0.25 - 0.82) and former heroin use with fewer decayed teeth (IRR= 0.61, 95% CI: 0.41 - 0.97). The associations for marijuana and cocaine were not statistically significant after adjustment.
Conclusion:
Illicit drug use shows heterogenous associations with the development of caries; however, the impact differs according to the type of drug. The findings of this study emphasize the requirement for comprehensive dental management and integration of substance-abuse screening within oral healthcare services.
関連する概念動画
Non-Oral Extravascular Drug Absorption Routes
Lipophilic drugs that are stable at salivary pH (6) and exhibit minimal binding to the oral mucosa are absorbed more...
Data Reporting and Recording
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Secondary Active Transport
Analysis of Population Pharmacokinetic Data
Secondary Healthcare System

