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Updated: Jan 24, 2026

Generating Chimeric Zebrafish Embryos by Transplantation
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内生レトロウイルスは,ヒトの早期胚発達の強化のために,異種キメリックRNAを合成する

Yangquan Xiang1,2, Yuli Qian1,2, Zhengyi Li1

  • 1Institute of Medical Genetics and Development, Key Laboratory of Reproductive Genetics (Ministry of Education) and Department of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Science (New York, N.Y.)
|January 22, 2026
PubMed
まとめ

ジゴティックゲノム活性化 (ZGA) の障害はヒト胚の発達を阻害する. レトロウイルスMLT2A1はZGAにとって極めて重要で,キメリックRNAとHNRNPUを通じて遺伝子発現と胚形成を促進する.

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