サラブレッドアスリートにおけるトレーニング後のマイクロRNAおよび標的遺伝子の調節
Thiago Maués Amaral1, Priscilla do Carmo de Azevedo Ramos2, Roberta de Araújo Silva2
1Laboratory of Human and Medical Genetics, Federal University of Pará, PA, Brazil.
Introduction:
In the context of Brazilian equestrian sports, the Quarter Horse (QH) breed has the third largest population of registered horses and stands out for its numerous abilities in various disciplines. Studies on equine health and athletic performance parameters are scarce, especially involving molecular markers.
Objective/Methods:
This study aimed to investigate the differential expression of microRNAs and target genes involved in metabolic pathways of exercise and to assess hematological and clinical changes in 10 horses (Equus caballus Linnaeus) of the QH breed under different physiological conditions. Horses of both sexes, aged 6 years, weighing between 400 and 513 kg (442,3kg Mean), with the same housing, feeding, and training management throughout the experiment. The horses were subjected to a race with obstacle deviation.
Results:
The results of clinical, hematological, and molecular parameters showed significance (p<0.05) after exercise. These bioindicators demonstrate that equine physiology is modulated after training, with an increase in oxygen transport, oxygen metabolism for energy conversion, and post-training recovery induced by the inflammatory response to aerobic exercise.
Conclusions:
The revealed data should be considered important parameters for animal health management and for assessing the physiological performance of horses during training, especially for athletic QH horses raised in the Amazon region.
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