関連する実験動画

Updated: Jan 24, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Published on: May 28, 2019

ST上昇を伴う心筋梗塞患者における院前ショックチーム導入の効果

Abdulrahman Arabi¹, Mhd Baraa Habib¹, Mohamed Salah Abdelghani¹

¹Cardiology Department, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.

Current problems in cardiology

|January 22, 2026

要旨

Background:

Cardiogenic shock (CS) complicating ST-segment elevation myocardial infarction (STEMI) is associated with high mortality rates. While in-hospital shock teams have shown benefits, the impact of pre-hospital shock team activation remains underexplored.

Methods:

In July 2022, our high-volume primary percutaneous coronary intervention (PPCI) center serving the entire state population implemented a pre-hospital shock team. This multidisciplinary team comprises an emergency department physician, cardiac intensivist, interventional cardiologist, cardiac anesthesiologist, and extracorporeal membrane oxygenation (ECMO) specialists. Activation criteria include hypotension, tachycardia or bradycardia, acute heart failure, significant ST-elevation, ventricular arrhythmias, or elevated lactic acid levels. We compared mortality rates 18 months before and after implementation.

Results:

Before implementation, 1,605 STEMI patients were admitted, compared to 1,735 after implementation. Of these, 217 (12%) met shock team activation criteria. Early Hospital mortality (in ED and in Cath lab) and Overall-hospital mortality rates significantly declined following implementation (1.2% vs. 0.3%, p=0.03; and 2.1% vs. 3.3%, p=0.02, respectively).

Conclusion:

This study suggests that pre-hospital shock team implementation is associated with a significant reduction in STEMI mortality.

キーワード:

心原性ショック ECMO 早期リスク層別化救急医療サービス死亡率学際的ケア院前活性化 primary PCI ST上昇心筋梗塞ショックチーム

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Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Published on: October 14, 2016

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