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Updated: Jan 24, 2026

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry
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Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry

Published on: July 20, 2016

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タンパク質の任意の部位で迅速かつ高生産性のディスルファイド生物結合

Dastgir Shakil Shaikh1, Suman Rajput1, Dimpy Kalia1

  • 1Department of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal, Bhopal Bypass Road, Bhauri, Bhopal, 462066 Madhya Pradesh, India.

Journal of the American Chemical Society
|January 23, 2026
PubMed
まとめ

新しいStapleAldとLAP-StapleAldの技術により,二硫化結合を通じて効率的なタンパク質の生物結合が可能になります. これは既存の方法の限界を克服し,広範なアプリケーションのためのサイト固有のタンパク質とペプチドのラベリングを可能にします.

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