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歯肉の脱色素沈着に対するビタミンCの効果:システマティックレビュー
Bushra Aljahdali1, Rana Dahlan2
1Department of Periodontology, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia, kau.edu.sa.
International journal of dentistry
|January 23, 2026
まとめ
アスコルビン酸(ビタミンC)は、歯肉の脱色素沈着に対して効果的かつ安全な治療法として有望視されている。歯肉の着色過剰の低侵襲治療におけるプロトコルの標準化には、さらなる研究が必要である。
科学分野:
- 歯周病学
- 皮膚科学
- 審美歯科
背景:
- 歯肉の着色過剰は美容上の懸念事項である。
- 歯肉の脱色素沈着のための低侵襲治療が求められている。
- アスコルビン酸(ビタミンC)は、その潜在的な治療効果について検討されている。
研究 の 目的:
- 歯肉の脱色素沈着におけるアスコルビン酸(ビタミンC)の有効性を評価すること。
- 歯肉の着色過剰の管理のための低侵襲な選択肢としてビタミンCを評価すること。
主な方法:
- 8件の研究(5件のRCT、3件の症例シリーズ)のシステマティックレビュー。
- 主要な電子データベースを横断して検索を実施。
- 主に粘膜内注射(メソセラピー)である様々なビタミンCの適用技術の分析。
主要な成果:
- 全ての研究で、ビタミンC療法後(例:Dummett-Gupta口腔色素沈着指数を使用)の歯肉色素沈着の改善が示された。 メソセラピーは、局所ゲルよりも迅速かつ顕著な結果をもたらした。 研究の異質性にもかかわらず、患者の満足度が高く、副作用が最小限であることが報告された。
結論:
- アスコルビン酸(ビタミンC)は、歯肉の脱色素沈着に対する有望で安全かつ低侵襲な治療法である。
- 標準化された臨床プロトコルと長期的なランダム化試験が必要である。
- 比較有効性を確立し、一貫した結果を確保するためには、さらなる研究が必要である。
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