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Updated: Jan 24, 2026

Transcranial Pulse Stimulation for Alzheimer's Patients

Transcranial Pulse Stimulation for Alzheimer's Patients

Published on: April 4, 2025

白色ネイルポリッシュ着用患者における酸素飽和度保持下の脈拍数変動を伴う脈拍オキシメトリ：症例報告

Akhtar Purvez^1,2

¹Clinical Research, Momentum Medical Research, Charlottesville, USA.

|January 23, 2026

Abstract:

Pulse oximetry is widely used for noninvasive monitoring of oxygen saturation (SpO₂) and pulse rate. Because the pulse rate displayed by a pulse oximeter is derived from the peripheral photoplethysmographic waveform, it can be affected by artifact even when oxygen saturation appears normal. We report a case of an asymptomatic patient wearing white nail polish who demonstrated stable, normal SpO₂ values yet markedly erratic pulse rate readings on pulse oximetry, fluctuating rapidly between bradycardic and tachycardic ranges. Concern for arrhythmia prompted a 12‑lead electrocardiogram, which showed a normal sinus rhythm. This report highlights a practical diagnostic pitfall: nail cosmetics may have little effect on SpO₂ yet still destabilize pulse waveform detection and generate misleading pulse rate values, leading to unnecessary evaluation and erroneous clinical conclusions.

キーワード:

不整脈模倣診断エラーネイルポリッシュ患者安全フォトプレチスモグラフィーパルスオキシメトリ

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関連する概念動画

Pulse Oximetry

Pulse Oximetry

Pulse oximetry, or SpO2, is a non-invasive method for continuously monitoring arterial oxygen saturation (SaO2). This procedure involves attaching a probe or sensor to the patient's fingertip, forehead, earlobe, or nose bridge. The sensor works by detecting changes in oxygen saturation levels through light signals generated by the oximeter and reflected by the pulsing blood under the probe.
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...

Increased pulse rate

Increased pulse rate

Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...

Decreased pulse rate

Decreased pulse rate

Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...

Pulse

Pulse

When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...

Pulse

Pulse

The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...

NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences

NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences

A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.