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Updated: Jan 25, 2026

Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO
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Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO

Published on: December 28, 2019

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ドメイン交換とアクティブサイト変異による3つの二機能性セステルペン合成と製品プロフィールに関する構造的洞察

Zhenyu Lei1, Ruiqing Lyu2, Wenlong Song1

  • 1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing 100191, China.

Journal of the American Chemical Society
|January 23, 2026
PubMed
まとめ

研究者らは,セステルテルペン生成に関与する二機能性テルペン合成酵素 (TSs) の新しい構造を発見した. これらの発見は新しいアーキテクチャと酵素機能を明らかにし,新しいテルペン分子の設計に役立ちます.

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