統合されたToxCast™データ、機械学習、および実験的検証による脂肪肝誘発性化学物質の優先順位付け
Xiaoliu Shi1, Lingbing Jin1, Xiaochun Ma1
1School of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Environment international
|January 23, 2026
まとめ
脂肪肝誘発性化学物質の特定は、代謝性疾患の調節に不可欠である。本研究では、ハイスループットスクリーニングデータと予測モデリングを統合し、脂肪肝疾患を引き起こす化学物質の優先順位付けを行い、インビボおよびインビトロ実験でその結果を検証する。
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