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Updated: Jan 28, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

急性リンパ性白血病の新たな治療法としてのフェロプトーシス

Jiongping Han¹, Yifan Yang¹, Yuxin Wei¹

¹Department of Hematology, Shaoxing People's Hospital, The First Hospital of Shaoxing University, Shaoxing, China.

Frontiers in oncology

|January 26, 2026

Abstract:

Acute lymphoblastic leukemia poses substantial challenges in therapeutic management. As a novel form of programmed cell death, ferroptosis has emerged as a promising research direction in cancer therapy. Studies have emphasized the pivotal role of ferroptosis in ALL, indicating that targeting this pathway could provide a novel therapeutic strategy. This article systematically reviews the molecular regulatory mechanisms of ferroptosis in ALL and explores its potential clinical applications in the treatment and prognostic evaluation of the disease.

キーワード:

急性リンパ性白血病フェロプトーシスフェロプトーシス誘導薬フェロプトーシス関連遺伝子分子メカニズム

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Isolation of the Side Population in Myc-induced T-cell Acute Lymphoblastic Leukemia in Zebrafish

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