Biological Matrix-Assisted Apexification: A Case Report Using PRF and MTA in Immature Necrotic Teeth
Shwetana Kurundkar1, Adityasingh Patel1, Manoj Chandak1
1Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College and Hospital, Wardha, Maharashtra, India, dmimsu.edu.in.
Case reports in dentistry
|January 26, 2026
まとめ
Treating infected immature teeth requires inducing an apical barrier. Platelet-rich fibrin (PRF) combined with mineral trioxide aggregate (MTA) shows promise for apexification, though disinfection may require multiple visits.
科学分野:
- 歯科
- 再生歯科
- 生体材料
背景:
- 感染した非生きた未熟な永久歯の治療は、自然な根尖狭窄がないため課題がある。
- 水酸化カルシウムを用いた従来の根尖形成術は、治療期間が長く、予後が予測不可能である。
- 三酸化鉱物アグリゲート(MTA)は、根尖バリアを誘導するための、より迅速で予測可能な代替手段を提供する。
研究 の 目的:
- MTAとPRFを併用した根尖形成術におけるフィブリン富血小板(PRF)を生物学的マトリックスとして使用する症例報告を提示すること。
- 未熟な壊死性歯におけるこの併用療法の有効性を評価すること。
主な方法:
- 未熟な壊死性歯の歯内療法を詳述した症例報告。
- 根尖形成術のために、フィブリン富血小板(PRF)と併せて三酸化鉱物アグリゲート(MTA)を使用した。
- 持続的な浸出液のため、徹底的な消毒を優先し、複数回の来院によるアプローチを採用した。
主要な成果:
- MTAとPRFの組み合わせを未熟な壊死性歯の根尖形成術に用いた。
- 持続的な浸出液のため、適切な消毒には段階的な治療プロトコルが必要であった。
- 消毒環境が達成された後に最終的な根管充填を行った。
結論:
- フィブリン富血小板(PRF)は、根尖形成術においてMTAと併用して生物学的な内部マトリックスとして機能することができる。
- 単回での来院が当初は考慮されたが、適切な消毒を達成することが最優先であり、複数回の来院が必要となる可能性がある。
- このアプローチは、未熟な壊死性歯の管理に有望な代替手段を提供する。
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