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Updated: Jan 28, 2026

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Published on: May 17, 2022

生体応用向け接着性ハイドロゲルの設計原理

Zhuhao Tan¹, Wenjing Song¹, Li Ren¹

¹School of Materials Science and Engineering, National Engineering Research Center for Tissue Restoration and Reconstruction, Key Laboratory of Biomedical Engineering of Guangdong, Province Innovation Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, P. R. China. phsongwj@scut.edu.cn.

Materials horizons

|January 27, 2026

Abstract:

Adhesive hydrogels have great potential for application in the biomedical field. Currently, for clinical applications, adhesive hydrogels need to have the following characteristics: good biocompatibility, strong tissue adhesion, highly adaptable tissue specificity and multifunctionality, which are also included in the design principles of current adhesive hydrogels. When targeting different types of diseases in different tissues, adhesive hydrogels need different degrees of attention to these four key properties according to the characteristics of the pathological microenvironment of the tissue. In this regard, this article reviews the clinical disease characteristics of different tissues, and correspondingly introduces the considerations in the design process of adhesive hydrogels for this type of disease and application, in order to deepen the understanding of the design principles of adhesive hydrogels in biomedical applications.

キーワード:

接着性ハイドロゲル生体応用組織工学ドラッグデリバリー再生医療バイオマテリアル

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