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Updated: Jan 28, 2026

Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
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Published on: February 28, 2021

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CRISPRを介したデュアルシグナル増幅ベースのバイオセンサーによるmiRNA測定のための工学的設計

Zhixian Liang1,2, Jie Zhang1, Shaohui Zhang1

  • 1National Engineering Research Center for Healthcare Devices & Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510316, China.

Biosensors
|January 27, 2026
PubMed
まとめ

本研究では、がんの重要なバイオマーカーであるmiRNA-21を検出するための新規電気化学バイオセンサーを発表する。この高度なシステムは、がんの早期診断と治療モニタリングの改善につながる、高感度かつ特異的な検出を提供する。

キーワード:
CRISPRTdT媒介重合ラベリングmiRNA-21自己プライミングヘアピン等温増幅

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