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関連する概念動画

Global Climate Change01:50

Global Climate Change

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Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
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Lung Capacity01:47

Lung Capacity

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The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
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Work Done During Volume Change01:17

Work Done During Volume Change

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In mechanics, work is done on an object when the force acting on it displaces the object. In thermodynamics, work done on a system can be estimated when the system's volume changes during any thermodynamic process.
Consider a gas confined to a cylinder fitted with a movable piston at one end. If the gas expands from volume V1 to volume V2, it exerts a force on the piston, such that the piston moves by a distance dr.
The work done by the gas on the piston can be expressed as
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Net Change Theorem01:22

Net Change Theorem

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The Net Change Theorem is a fundamental principle in calculus that establishes a direct relationship between a function’s rate of change and its accumulated change over an interval. Mathematically, it states that the definite integral of a function's derivative over a given interval [a,b] yields the net change in the original function:This theorem has significant applications in various real-world scenarios, including physics, economics, and engineering. A particularly useful application...
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Standard Entropy Change for a Reaction03:00

Standard Entropy Change for a Reaction

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Entropy is a state function, so the standard entropy change for a chemical reaction (ΔS°rxn) can be calculated from the difference in standard entropy between the products and the reactants.
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Le Chatelier's Principle: Changing Temperature02:19

Le Chatelier's Principle: Changing Temperature

35.3K
Consistent with the law of mass action, an equilibrium stressed by a change in concentration will shift to re-establish equilibrium without any change in the value of the equilibrium constant, K. When an equilibrium shifts in response to a temperature change, however, it is re-established with a different relative composition that exhibits a different value for the equilibrium constant.
To understand this phenomenon, consider the elementary reaction:
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Updated: Jan 28, 2026

Real-time X-ray Imaging of Lung Fluid Volumes in Neonatal Mouse Lung
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肺カルチノイド - 実践を変える時

Ana Rodrigues1,2, Nuno Coimbra2,3,4, Inês Lucena Sampaio5

  • 1Department of Medical Oncology, Portuguese Oncology Institute of Porto, 4200-072 Porto, Portugal.

Current oncology (Toronto, Ont.)
|January 27, 2026
PubMed
まとめ
この要約は機械生成です。

この肺カルチノイドの研究では、診断と治療のアプローチが様々であることがわかり、ケアの標準化が必要であることが強調されました。実世界のデータは、これらのまれな神経内分泌腫瘍の管理におけるギャップを明らかにしています。

キーワード:
肺カルチノイド神経内分泌腫瘍実世界のデータ後ろ向き研究

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関連する実験動画

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科学分野:

  • 腫瘍学
  • 肺医学
  • 核医学

背景:

  • 肺カルチノイドは、まれな神経内分泌腫瘍（NET）であり、肺がんの1〜2％を占めます。
  • 臨床管理は、NET固有のガイドラインではなく、一般的な肺がんプロトコルに従うことがよくあります。

研究 の 目的:

  • 肺カルチノイドに関する12年間の実世界の経験を分析すること。
  • 総合がんセンターにおける診断、治療、およびフォローアップケアのギャップを特定すること。

主な方法:

  • 肺カルチノイドの成人患者129人を対象とした後ろ向き観察コホート研究。
  • 収集されたデータ：人口統計、臨床症状、画像（FDG-PET/CT、SSTR-PET/CT）、および治療。
  • 収集されたデータの記述的分析。

主要な成果:

  • ほとんどの患者（65.1%）は早期の病期で提示されました。17.1%はステージIVでした。
  • 手術は患者の78.3%の主要な治療法でした。
  • 診断画像における異質性が認められ、典型的なカルチノイドでもFDG-PET/CTが頻繁に使用されました。

結論:

  • 実世界のデータは、肺カルチノイドの診断経路の異質性と標準化されていないフォローアップを明らかにしています。
  • 典型的なカルチノイドにおけるFDG-PET/CTの過剰な使用が特定されました。
  • 管理を標準化するための専用の学際的な肺NETボードと参照センターの必要性。