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Updated: Jan 28, 2026

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram

Published on: July 7, 2023

腰痛と倦怠感を訴える44歳男性

John E Dobbs¹, Margaret D Krasne¹, Rakhi P Naik¹

¹from the Internal Medicine Residency Program and the Sections of Infectious Diseases, Hematology, and Pathology of Johns Hopkins Hospital.

|January 27, 2026

Abstract:

AbstractMorning Report is a time-honored tradition where physicians-in-training present cases to their colleagues and clinical experts to collaboratively examine an interesting patient presentation. The Morning Report section seeks to carry on this tradition by presenting a patient's chief concern and story, inviting the reader to develop a differential diagnosis and discover the diagnosis alongside the authors of the case. This report discusses the story of a 44-year-old man who sought evaluation for back pain and weakness. Using questions, physical examination, and testing, an illness script for the presentation emerges. As the clinical course progresses, the differential is refined until a final diagnosis is made.

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Weak Base Solutions

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As a result, there is no simple...

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Titration of a Weak Acid with a Strong Base

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In titrating a weak acid with a strong base, different calculation methods are applied at various stages. Initially, the pH of a weak acid like acetic acid is calculated using its dissociation constant (Ka) and an ICE table. Upon addition of a strong base such as sodium hydroxide, a buffer forms, and its pH is determined using the Henderson-Hasselbalch equation. As more base is added and the titration reaches the halfway point, the pH becomes equal to the pKa of the acid, indicating equal...