心不全患者の機能状態を鑑別するGlittre-ADLテストのカットオフ値

The Glittre activity of daily living (TGlittre) is a functional test that aligns with daily tasks, clinically useful, and is well-tolerated by patients.

The study aimed to establish the cut-off point for TGlittre test corresponding to the six-minute walk test (6MWT) threshold value of 400 m for determining impaired functional status in heart failure (HF) cases.

In the cross-sectional study, seventy-eight HF cases (mean age:63.61±11.55, 67.9 % male, LVEF: 35.41±7.60 %, NYHA FC II: 62.8%, FCIII: 37.2%) performed the 6MWT and TGlittre test in a random order. Also, each patient was administered with the International Physical Activity Questionnaire-Short Form (IPAQ-SF) and Minnesota Living with Heart Failure Questionnaire (MLHF-Q) questionnaires. The cut-off value for the TGlittre test was determined with Receiver operating characteristics analysis.

The equivalent TGlittre cut-off for the <400 m 6MWT threshold was 5.05 minutes (sensitivity: 88%, specificity: 81%, and area under the curve: 0.92(95 % confidence interval 0.87-0.98). The participants performing ≥5.05 minutes had lower levels of physical activity and higher MLHF-Q scores. Furthermore, the most of them were in NYHA FCIII (51.2%), and the mean LVEF % (33.12±7.75) was lower in this group.

5.05 minutes is a sensitive and specific cut-off point for TGlittre test in identifying impaired functional status in HF populations. The determined cut-off point also indicates a deterioration in the clinical features of the cases. This study suggests the TGlittre test as a clinically useful, objective, test for determining functional status in the HF population, including elderly patients.