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関連する概念動画

RNA Structure01:23

RNA Structure

79.0K
Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...
79.0K
RNA Structure01:19

RNA Structure

7.5K
The basic structure of RNA consists of a string of ribonucleotides attached by phosphodiester bonds. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA) involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three...
7.5K
Structural Protein Function01:56

Structural Protein Function

29.9K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
29.9K
Fruit Development, Structure, and Function01:58

Fruit Development, Structure, and Function

25.2K
Fruits form from a mature flower ovary. As seeds develop from the ovules contained within, the ovary wall undergoes a series of complex changes to form fruit. In some fruits, such as soybeans, the ovary wall dries; in other fruits, such as grapes, it remains fleshy. In some cases, organs other than the ovary contribute to fruit formation; such fruits are called accessory fruits.
25.2K
Local Anesthetics: Chemistry and Structure-Activity Relationship01:30

Local Anesthetics: Chemistry and Structure-Activity Relationship

6.6K
Local anesthetics (LAs) are drugs that induce a temporary loss of sensation in a limited body area, preventing pain. Cocaine was the first local anesthetic discovered in the late 19th century. Cocaine is a benzoic acid ester obtained from the leaves of coca shrubs and was often used for its psychotropic effects. Cocaine was first isolated in 1860 by Albert Niemann. Sigmund Freud studied the physiological actions of cocaine. Carl Koller later introduced it into clinical practice in 1884 as a...
6.6K
Cholinergic Antagonists: Chemistry and Structure-Activity Relationship01:29

Cholinergic Antagonists: Chemistry and Structure-Activity Relationship

2.8K
Cholinergic antagonists bind to cholinergic receptors and limit the effects of acetylcholine and other cholinergic agonists. Based on the specific cholinergic receptor affinity, these antagonists are classified as muscarinic or nicotinic. Anticholinergics interrupt parasympathetic innervations while sympathetic innervations remain uninterrupted. Muscarinic antagonists are also called 'muscarinic antagonists', 'antimuscarinics', or 'parasympatholytics'. Nicotinic...
2.8K

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関連する実験動画

Updated: Jan 29, 2026

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
14:37

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles

Published on: July 6, 2012

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ポリアニオン化学による内部からのRNAナノ粒子構造/機能のエンジニアリング

Lijun Hu1,2, David J Peeler1,2,3, Tianyi Jin4

  • 1Kavli Institute for Nanoscience Discovery, Department of Physiology, Anatomy and Genetics, Department of Engineering Science, University of Oxford, Oxford OX1 3QU, United Kingdom.

ACS nano
|January 27, 2026
PubMed
まとめ

研究者らは、強化された核酸送達のために特定のポリアニオンを使用して新しい三成分ポリエレクトロライトナノ粒子(TNP)を設計しました。これらのTNPは、脂質ナノ粒子に代わる有望な選択肢を提供する、安定性と標的送達を向上させています。

背景:

  • 脂質ナノ粒子(LNP)は核酸送達に一般的ですが、三成分ポリエレクトロライトナノ粒子(TNP)のようなポリマー代替物は標的送達の可能性を提供します。
  • TNPの安定性、タンパク質結合、およびトランスフェクション効率におけるポリアニオン化学の役割を理解することは、高度な送達システムの開発にとって重要です。

結論:

  • ポリアニオンエンジニアリングは、効率的なRNA送達のためのTNPの構造と機能を制御するための鍵となります。
キーワード:
PET-RAFTSANSハイスループット分子動力学自己増幅RNA構造/機能

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Thermochemical Studies of NiII and ZnII Ternary Complexes Using Ion Mobility-Mass Spectrometry
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Thermochemical Studies of NiII and ZnII Ternary Complexes Using Ion Mobility-Mass Spectrometry

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関連する実験動画

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  • 本研究は、RNA送達における生物学的障壁を克服するためのpH応答性ナノ粒子のハイスループットエンジニアリングのフレームワークを確立します。
  • 化学的に多様なポリアニオンは、標的核酸送達システムを開発するための調整可能なプラットフォームを提供します。