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Regulated Protein Degradation02:58

Regulated Protein Degradation

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It is vital to regulate the activity of enzymatic as well as non-enzymatic proteins inside the cell. This can be achieved either through creating a balance between their rate of synthesis and degradation or regulating the intrinsic activity of the protein. Both these regulation mechanisms play an essential role in the normal functioning of cells.
Protein degradation plays two important roles in the cells. It helps to protect cells from misfolded or damaged proteins before they lead to a...
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Regulated Protein Degradation02:58

Regulated Protein Degradation

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Proteins: From Genes to Degradation02:11

Proteins: From Genes to Degradation

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Within a biological system, the DNA encodes the RNA, and the nucleotide sequence in the RNA further defines the amino acid sequence in the protein. This is referred to as “The Central Dogma of Molecular Biology” - a term coined by Francis Crick.  Central dogma is a firm principle in biology that defines the flow of genetic information within any life form. The two fundamental steps in central dogma are - transcription and translation.
Transcription is the synthesis of RNA...
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Proteins: From Genes to Degradation02:11

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Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
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Impact Loading01:19

Impact Loading

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Impact loading occurs when a moving object collides with a stationary structure, such as a rod with a uniform cross-sectional area fixed at one end. Under these conditions, the rod absorbs the kinetic energy from the striking object, leading to deformation and subsequent stress development. As the rod returns to its original position and reaches maximum stress, the absorbed energy, initially manifested as kinetic energy, transforms entirely into strain energy.
In cases of elastic deformation,...
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アミラーゼ分解性、銅含有デンプンナノ粒子を用いた細菌標的化

Nathan A Jones1, Usha Kadiyala2, Benjamin Serratos3

  • 1Program in Macromolecular Science & Engineering, University of Michigan, Ann Arbor, MI 48108, USA.

Antibiotics (Basel, Switzerland)
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新規ナノ粒子は、細菌表面電荷と栄養環境を標的として抗生物質耐性と戦います。これらの代謝応答性銅デンプン粒子は、黄色ブドウ球菌に対して抗菌活性を高めました。

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バチルスサブチリス黄色ブドウ球菌アミラーゼ銅ナノ粒子エレクトロハイドロダイナミックジェッティング代謝応答性デンプンナノ粒子

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