関連する実験動画

Updated: Jan 29, 2026

The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila

The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila

Published on: December 14, 2020

中年以降から老年期における睡眠効率と睡眠薬の効果の相違：エピソード記憶への影響

Suhani Amin¹, Dokyung Yoon¹, Rahul Naveen¹

¹The Davis School of Gerontology, University of Southern California, Los Angeles, CA, United States.

Frontiers in sleep

|January 28, 2026

要旨

Objectives:

Different aspects of sleep quality are known to decline with age, and these changes have been shown to impact performance across multiple cognitive domains. However, despite a growing body of literature, the impact of changes to quality of sleep on episodic memory remains elusive, with some studies finding effects and others failing to find a relation.

Methods:

In this study, participants [N = 173, mean age = 65.30, range = [45-88]], completed the Pittsburgh Sleep Quality Index as well as three episodic memory tests (verbal and visual episodic memory and pattern separation).

Results:

We found that worse sleep efficiency was associated with worse overall episodic memory. Further, medication use had a positive effect on verbal, pattern separation, and overall episodic memory. Findings occurred in an age-dependent manner.

Conclusions:

These results underscore the complexity of sleep-memory interactions and suggest that certain aspects of episodic memory may be more sensitive to specific components of sleep quality than others, particularly as individuals age.

キーワード:

加齢効率エピソード記憶薬物療法睡眠

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