睡眠の質と補助生殖技術の結果との関連性:メタアナリシス
1Department of Reproductive Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Archives of gynecology and obstetrics
|January 28, 2026
まとめ
良好な睡眠の質は、補助生殖技術(ART)を受けている個人の臨床妊娠率および着床率を向上させる。出生率に対する影響については、さらなる研究が必要である。
科学分野:
- 生殖医学; 睡眠科学; 臨床研究
背景:
- 睡眠の質は健康状態と関連しているが、補助生殖技術(ART)への影響は不明である。; 本研究では、睡眠の質とARTの成功率との関連性を系統的に評価する。
研究 の 目的:
- 睡眠の質と補助生殖技術(ART)の結果との関連性を系統的に評価すること。
主な方法:
- PubMed、Embase、Web of Science、およびCochrane Libraryを対象とした2025年4月1日までの系統的文献検索。; Newcastle-Ottawa Scale(NOS)を用いた観察研究の質的評価。; Stata 15.0ソフトウェアを用いたメタアナリシス。
主要な成果:
- 良好な睡眠の質は、臨床妊娠率を有意に増加させた(OR=1.53、95% CI [1.16, 2.03])。; 感度分析により、異質性に対処した後の安定した結果が確認された。; 良好な睡眠は、有意に増加した胚着床率とも関連していた(OR=1.41、95% CI [1.04, 1.92])。; 出生率には統計的な差は認められなかった(OR=0.84、95% CI [0.44, 1.61])。
結論:
- 良好な睡眠の質は、ARTにおける臨床妊娠率および着床率の向上と正の相関がある。; 出生率に対する睡眠の質の影響については、さらなる調査が必要である。
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