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Updated: Jan 30, 2026

A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis
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腸内マクロファージは,腸-脳軸に沿ってシヌクレイン病変を調節する

Sebastiaan De Schepper1,2, Viktoras Konstantellos3, James A Conway3

  • 1UK Dementia Research Institute, University College London, London, UK. sebastiaan.deschepper@uantwerpen.be.

Nature
|January 28, 2026
PubMed
まとめ

Muscularisマクロファージは,腸の神経系でパーキンソン病 (PD) の病理を誘発する. これらの細胞をターゲットにすることで,病理の広がり,神経変性,および運動欠陥を軽減し,早期のPDバイオマーカーを潜在的に提供します.

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