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Updated: Jan 31, 2026

Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides

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患者中心の臨床試験の開発：患者の視点を組み込むことの意味

Deena Sukhon^1,2,3, Sarah E Bradley^1,2, Alexander K Hallway^1,2

¹Department of Surgery, Michigan Medicine, Ann Arbor, Michigan.

Annals of surgery

|January 30, 2026

Abstract:

Patient-centered clinical trials are vital for ensuring surgical research reflects patient priorities. Using groin hernia as a case study, this exploratory qualitative study explored female patients' perspectives on research priorities and trial participation. Thirty-four interviews revealed strong interest in nonoperative options, willingness to participate in trials, and emphasis on outcomes such as pain, recovery, and quality of life, highlighting the need for inclusive, patient-informed trial design.

キーワード:

臨床試験女性患者鼠径ヘルニア患者エンゲージメント患者アウトカム患者中心の研究試験デザイン

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