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Updated: Jan 31, 2026

mRNA Interactome Capture from Plant Protoplasts
Published on: July 28, 2017
植物におけるmRNAアセチル化の新たな役割
Jie Zhao1, Changhua Zhu1, Xiaoyun Song1
1College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, P.R. China.
Abstract:
N4-acetylcytidine (ac4C) is a conserved acetylation modification on messenger RNA (mRNA) recently identified in plants. It is deposited by the N-ACETYLTRANSFERASE FOR CYTIDINE IN RNA (ACYR) protein, which is homologous to mammalian N-ACETYLTRANSFERASE (NAT10) (Wang et al., 2023; Li et al., 2023). Here, we describe the defining features and functional landscape of ACYR-dependent ac4C marks, their effects on mRNA expression, stability, splicing, and translation, and their roles in leaf development (Wang et al., 2023), photosynthesis (Zhao et al., 2025; Cai et al., 2025), thermosensory flowering (Wu et al., 2025), and plant defense (Lu et al., 2024). We highlight current methods for ac4C profiling and discuss future directions in ac4C research.mRNA acetylation occurs in plants.
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