高齢患者における薬剤関連問題の特定と解決
Meghan E Peterson1, Joanna L Stollings1, E Wesley Ely1,2
1Vanderbilt University Medical Center, Nashville, TN, USA.
Hospital pharmacy
|January 30, 2026
まとめ
高齢患者は、加齢に伴う変化や併存疾患により、薬物療法上の問題のリスクが高いです。薬剤師、医師、および先端実践提供者(APP)を含む多職種チームアプローチは、薬物管理と患者の安全を最適化するために不可欠です。
科学分野:
- 老年医学;臨床薬学;内科学
背景:
- 加齢は生理学的変化をもたらし、薬物反応に影響を与え、高齢患者の薬剤関連問題のリスクを高めます。;併存疾患と多剤併用は高齢者によく見られ、薬物療法レジメンとアドヒアランスを複雑にします。;高齢患者における薬物療法上の問題には、不適切な薬物使用やアドヒアランスの問題が含まれ、複雑なレジメンや費用によってしばしば悪化します。
研究 の 目的:
- 高齢患者における加齢に伴う主要な生理学的変化を説明すること。;高齢者の薬物療法管理における薬剤師、医師、および先端実践提供者(APP)の重要な役割を強調すること。;高齢者の薬物療法レジメンの評価と最適化の方法を議論すること。
主な方法:
- 薬物療法に影響を与える高齢者の生理学的変化のレビュー。;薬物療法上の問題に対処する上での多職種チーム(薬剤師、医師、APP)の役割の探求。;アメリカ老年医学会ビアーズ基準やSTOPP/STARTなどの評価ツールの議論。
主要な成果:
- 高齢患者は、加齢に伴う変化や併存疾患により、薬剤関連問題のリスクが高いです。;ケアコンティニュアム全体での協力的なアプローチが、成功する薬物療法管理に不可欠です。;薬剤師、医師、およびAPPは、薬物療法上の問題を積極的に特定、評価、解決する必要があります。
結論:
- 高齢患者の薬物療法を最適化するには、協調的で多職種的な努力が必要です。;定期的な薬物評価、照合、処方中止、アドヒアランスサポートは重要な戦略です。;エビデンスに基づいたツールを利用することは、適切な薬物選択と処方連鎖の防止に役立ちます。
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