頭蓋骨を透過する集束超音波渦の音響メタ表面による転写制御
1School of Engineering Medicine, Beihang University, Beijing 100191, China; Beijing Advanced Innovation Center for Biomedical Engineering, Beijing 100191, China; Shenzhen Institute of Beihang University, Shenzhen 518000, China.
Abstract:
Ultrasound vortices have rapidly expanded their applications to areas like particle trapping, contactless manipulation, acoustic communications. In ultrasonic imaging and therapy involving bone tissues, these vortex beams offer intriguing possibilities but transmitting them through bone (especially the skull) poses challenges. Traditional acoustic lenses were engineered to rectify skull-induced beam aberration, and their capacity was limited to generating only static ultrasound fields within the brain. To overcome this constraint, our study presents a novel method for transcranially steering focused ultrasound vortex using 3D printed binary acoustic metasurfaces (BAMs) with a thickness of 0.8 λ. We tackled the challenge of skull-induced phase aberration by computing the phase distribution via a time reversal technique, which concurrently enabled the generation of a steerable focused vortex inside an ex vivo human skull by adjusting the operating frequency. Both numerical and simulations experiments were conducted to validate the capabilities of BAMs. We further conducted numerical demonstrations of higher-order vortices (l=2-4) inside the skull using the BAM, confirming that the approach is extensible beyond the fundamental case. This development paves the way for designing cost-effective particle-trapping systems, facilitating clot manipulation, and applying acoustic-radiation forces and torques within or across bone structures, thus presenting a new frontier for potential biomedical applications.
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