Spatiotemporal acoustic meta-patches for multifactorial wound treatment
Zhuhao Wu1, Jingjing Gan1, Yuanjin Zhao1,2,3
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
Bioactive materials
|February 3, 2026
まとめ
A novel spatiotemporal acoustic meta-patch (STAMP) offers controlled multifactorial wound treatment. This ultrasound patch precisely regulates temperature, inflammation, and healing for enhanced therapeutic outcomes.
科学分野:
- Biomedical Engineering
- Materials Science
- Acoustics
背景:
- Ultrasound patches show diagnostic promise but lack precise therapeutic control.
- Current limitations hinder the integration of multi-effects for advanced wound care.
研究 の 目的:
- To introduce a spatiotemporal acoustic meta-patch (STAMP) for synergistic multifactorial wound treatment.
- To demonstrate STAMP's ability to precisely control ultrasound energy for therapeutic applications.
主な方法:
- Development of STAMP using acoustic metamaterial composites with reconfigurable interdigital transducers (IDTs).
- Utilizing an acoustic impedance matching layer for efficient ultrasound energy focusing and transport.
- Evaluating STAMP's effects on localized heating, bioactive agent delivery, and cell migration.
主要な成果:
- STAMP demonstrated precise spatial and temporal control over ultrasound energy delivery.
- The patch induced localized heating, enhanced bioactive agent delivery, and promoted cell migration.
- STAMP effectively modulated wound microenvironments, including temperature, inflammation, and wound closure.
結論:
- STAMP provides a proof-of-concept for enhanced multifactorial wound healing.
- Reconfigurable and multifunctional acoustic metamaterial patches offer new avenues for ultrasound-based therapeutics.
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