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Updated: Feb 4, 2026

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

Published on: March 14, 2013

乳児におけるPPI使用の治療的ジレンマ - もはやジレンマではない

Simran Aggarwal¹, Michael Rieder²

¹Department of Pediatrics, McMaster Children's Hospital, Hamilton, Ontario, Canada.

Paediatrics & child health

|February 3, 2026

Abstract:

While proton pump inhibitors (PPIs) are widely recognized for their effectiveness in treating gastroesophageal reflux disease in older children and adults, their use in infants is controversial due to the paucity of well-controlled studies demonstrating clear benefits. Furthermore, concerns about potential adverse effects, such as increased risks of gastrointestinal and respiratory infections, nutrient malabsorption and alterations in gut microbiota, complicate the decision-making process for health care providers and care givers. The current guidelines emphasize nonpharmacologic management for infantile reflux and recommend PPIs for very specific indications. Despite this, PPIs continue to be widely prescribed to infants.

キーワード:

小児 PPI 逆流

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P50 Sensory Gating in Infants

P50 Sensory Gating in Infants

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Quantified Assessment of Infant's Gross Motor Abilities Using a Multisensor Wearable

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Published on: May 17, 2024

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