関連する実験動画
Updated: Feb 4, 2026

07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
864
テントおよびテント下腫瘍に対する術前塞栓術
Satoshi Koizumi1, Shigeta Fujitani1, Takeru Hirata1
1Department of Neurosurgery, The University of Tokyo, Tokyo, Japan.
Journal of neuroendovascular therapy
|February 3, 2026
まとめ
テント腫瘍の術前塞栓術は、頭蓋底手術の安全かつ効果的な補助療法です。この手技は、腫瘍の血管新生と壊死を減少させ、合併症を最小限に抑えながら複雑な切除を支援します。
科学分野:
- 脳神経外科; 血管内治療; 血管神経学
背景:
- テントおよびテント下腫瘍は、深部位置と複雑な血管性のため、外科的課題を提示する。術前塞栓術は、これらの腫瘍の外科的転帰を改善するための補助療法となり得る。テント腫瘍に対する術前塞栓術の安全性と有効性に関するデータは限られている。
研究 の 目的:
- テント腫瘍に対する術前塞栓術の技術的配慮と転帰をレビューする。一連の患者における本手技の安全性と有効性を評価する。塞栓術の技術と供給動脈の分類を詳述する。
主な方法:
- テント腫瘍に対する29例の連続した術前塞栓術のレトロスペクティブレビュー。内側(MHT、ILT)、外側(中硬膜動脈、後頭動脈)、および下側(APA)の供給動脈を標的とする技術的アプローチの分析。技術的成功、使用された塞栓物質、および塞栓後の合併症の評価。
主要な成果:
- 技術的成功率は96.6%(29例中28例)。塞栓術は主にMHT/ILT(53.6%)およびAPA(21.4%)から行われ、複数の供給動脈が標的とされた(46.6%)。主な塞栓物質はN-ブチルシアノアクリレート(85.7%)、コイル(39.3%)、粒子(35.7%)であった。神経学的合併症は7.1%(29例中2例)で、主に脳神経麻痺であった。腫瘍壊死は60.7%で達成され、造影効果の消失は10.7%で認められた。
結論:
- テント腫瘍の術前塞栓術は、実行可能かつ効果的である。本手技は、専門知識をもって行われた場合、後続の外科的切除に実質的な利益をもたらす。複雑な頭蓋底手術において、許容可能なリスクが伴う。
関連する概念動画
Pulmonary Embolism I: Introduction
702
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
702
Pulmonary Embolism III: Nursing Management
439
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
439
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
448
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
448
Tumor Immunotherapy
1.9K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
1.9K
Tumor Progression
7.4K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.4K
The Tumor Microenvironment
7.8K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
7.8K

