Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

What is an Electrochemical Gradient?01:26

What is an Electrochemical Gradient?

127.9K
Adenosine triphosphate, or ATP, is considered the primary energy source in cells. However, energy can also be stored in the electrochemical gradient of an ion across the plasma membrane, which is determined by two factors: its chemical and electrical gradients.
The chemical gradient relies on differences in the abundance of a substance on the outside versus the inside of a cell and flows from areas of high to low ion concentration. In contrast, the electrical gradient revolves around an...
127.9K
Electrochemical Gradient and Channel Proteins: An Overview01:21

Electrochemical Gradient and Channel Proteins: An Overview

4.7K
An electrochemical gradient is a fundamental concept in biology and chemistry. It regulates the movement of ions across cell membranes. This movement is influenced by two factors:
The electrical gradient: The electrical gradient across cell membranes refers to the difference in electric charge between the inside and outside of a cell.  This difference drives the movement of ions towards or away from the cells. For instance, if the inside of the cell is more negatively charged relative to...
4.7K
Methods for Controlling Microbial Growth01:29

Methods for Controlling Microbial Growth

1.7K
Microbial growth control refers to various methods employed to inhibit, reduce, or eliminate microorganisms to ensure safety and hygiene across different settings. These methods are categorized based on the target environment and the level of microbial control required.Biocides are versatile agents designed to control microorganisms by either inhibiting their growth or outright killing them. These agents work through various physical, chemical, mechanical, or biological mechanisms. The...
1.7K
Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

896
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
896
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

891
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
891
Physical Methods for Controlling Microbial Growth: Temperature01:23

Physical Methods for Controlling Microbial Growth: Temperature

1.1K
Heat is a widely used method to control microbial growth by targeting and denaturing cellular proteins, thereby killing or inactivating microbes. This method's effectiveness is quantified using parameters such as the thermal death point (TDP), thermal death time (TDT), and decimal reduction time (D value). TDP represents the lowest temperature at which all microorganisms in a liquid suspension are eliminated within 10 minutes, whereas TDT is the time necessary to achieve sterilization at a...
1.1K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Resilient nanostructured bioanalytic microneedle longitudinally monitors preclinical renal and hepatic drug clearance and dysfunction.

Science translational medicine·2026
Same author

Electrochemical Control with High Spatiotemporal Resolutions for Extracellular pH Microenvironment.

ACS electrochemistry·2025
Same author

Automated Electroanalysis Accelerates the Discovery of Concerted Proton-Electron Transfer.

Journal of the American Chemical Society·2025
Same author

Sensitive Imaging of Electroactive Species in Plasmonic Electrochemical Microscopy Enabled by Nanoconfinement.

ACS electrochemistry·2025
Same author

Synthesis of [Os(bpy)<sub>2</sub>(py)(OH<sub>2</sub>)](PF<sub>6</sub>)<sub></sub> substituted pyridine complexes; characterization of a singly bridged H<sub>3</sub>O<sub>2</sub><sup>-</sup> ligand.

Dalton transactions (Cambridge, England : 2003)·2025
Same author

Tandem metabolic reaction-based sensors unlock in vivo metabolomics.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same journal

Proton-Gated Torsional Spring for Molecular Energy Storage.

Journal of the American Chemical Society·2026
Same journal

Topologically Programmed Dual-Channel Covalent Organic Frameworks Decouple Gas and Ion Fluxes for Acidic CO<sub>2</sub> Electroreduction.

Journal of the American Chemical Society·2026
Same journal

Plasmonic Re-Excitation Enables Superoxide-Mediated Ethane Conversion to Acetic Acid under Visible Light.

Journal of the American Chemical Society·2026
Same journal

Photocatalytic Controlled Halodefluorination of Perfluoroalkyl Compounds Using <i>N</i>-Arylphenothiazines.

Journal of the American Chemical Society·2026
Same journal

Photoinduced Disproportionation Enables Oxidative Addition of Aryl Iodides at a Gallium(I) Center.

Journal of the American Chemical Society·2026
Same journal

Biocatalytic C3 β-<i>O</i>-Glycosylation of Triterpenes and Sterols to Synthesize Natural and Unnatural Saponins.

Journal of the American Chemical Society·2026
関連記事をすべて見る

関連する実験動画

Updated: Feb 5, 2026

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
08:00

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation

Published on: October 4, 2024

1.1K

微生物の微環境を彫刻する: プログラム可能な電気化学的梯度による時空制御

Haiyuan Zou1, Yifan Gao2, Ziqi Ding1

  • 1Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California 90095, United States.

Journal of the American Chemical Society
|February 4, 2026
PubMed
まとめ
この要約は機械生成です。

電気化学は,pHと酸素 (O2) のような化学的梯度を生成することによって,微生物の微環境を正確に制御することを可能にします. この技術により,研究者は微生物の反応をリアルタイムで研究することができ,バイオフィルムと抗菌剤耐性に関する理解を深めることができます.

さらに関連する動画

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

6.6K
Electrochemically and Bioelectrochemically Induced Ammonium Recovery
09:50

Electrochemically and Bioelectrochemically Induced Ammonium Recovery

Published on: January 22, 2015

13.2K

関連する実験動画

Last Updated: Feb 5, 2026

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
08:00

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation

Published on: October 4, 2024

1.1K
Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

6.6K
Electrochemically and Bioelectrochemically Induced Ammonium Recovery
09:50

Electrochemically and Bioelectrochemically Induced Ammonium Recovery

Published on: January 22, 2015

13.2K

科学分野:

  • 微生物学と環境科学について
  • 生物物理化学 生物物理化学
  • バイオエンジニアリング バイオエンジニアリング

背景:

  • 微生物のコミュニティ,特にバイオフィルムは,異質性と抗微生物耐性を駆動する内生的な化学的梯度 (pH,酸素,反応性種) を生み出します.
  • これらのダイナミックな in vitro マイクロ環境を再現することは,微生物の研究において重要な課題となっています.
  • これらのグラデントを理解することは,微生物の生理学を理解し,新しい抗微生物戦略を開発するために不可欠です.

研究 の 目的:

  • 空間時間的な制御で微生物の微環境を彫刻するための強力なツールとして電気化学を強調する.
  • 化学的梯度を生成する電気化学的方法の使用における最近の進歩を in vitro で見直す.
  • 微生物の反応を研究するための電気化学的グラデント生成の可能性を実証する.

主な方法:

  • マイクロエレクトロッドに適用されるプログラム可能なポテンシャルを使用して,特定の化学品種を生成または枯渇させる.
  • pHのグラデーション,酸素 (O2),酸化窒素 (NO),活性酸素種 (ROS) を含む,ダイナミックで非侵襲的な化学風景を作成します.
  • 微生物コミュニティを取り巻く化学的環境を精密に制御するために,電気化学技術を使用します.

主要な成果:

  • 主要な化学物種 (pH,O2,NO,ROS) の制御されたグラデーションを電気化学的に生成する可能性を実証しました.
  • 自然な微生物の環境を模倣する様々な微生物環境の作成を in vitro で可能にしました.
  • 静的観測を超えて,リアルタイムで微生物の運動を分析する方法を提供した.

結論:

  • 電気化学的グラデント生成は,複雑な化学的景観における微生物の生命を研究するための変革的なアプローチを提供します.
  • この技術は,微生物の生理学,適応,応答メカニズムを調査するための前例のない制御を提供します.
  • 微生物の相互作用を理解し,ターゲットを絞った介入を開発するための新しい境界を開きます.