ニクラウ症候群:注射による合併症の症例報告
Ramya A1, Ambigai Ssk1, Adikrishnan Swaminathan1
1Dermatology, Venereology and Leprosy, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cureus
|February 4, 2026
まとめ
ニクラウ症候群は、痛みを伴う皮膚壊死を引き起こすまれな注射合併症です。この症例は、ジクロフェナク注射が潜在的な原因であることを強調しており、一般的な医療処置に伴うリスクを理解する必要性を強調しています。
科学分野:
- 医学
- 皮膚科学
- 薬理学
背景:
- ニクラウ症候群は、注射後に発生するまれではあるが重篤な有害事象です。
- 注射部位の痛み、虚血、および壊死として現れます。
- 注射可能な薬剤が普及しているため、その原因を理解することが重要です。
研究 の 目的:
- ジクロフェナク注射後のニクラウ症候群の症例報告。
- ニクラウ症候群の病因、臨床症状、および管理のレビュー。
主な方法:
- 筋肉内ジクロフェナク注射後に症状を呈した51歳男性患者の症例報告。
- ニクラウ症候群の原因、臨床的特徴、および治療に関する文献レビュー。
主要な成果:
- 患者は、注射後に痛み、皮膚の変色、壊死、および潰瘍を発症しました。
- ジクロフェナクが原因物質であると特定されました。
- 文献レビューにより、さまざまな薬剤がこの症候群を引き起こす可能性があることが確認されました。
結論:
- ニクラウ症候群は、ジクロフェナクのような一般的な薬剤であっても、注射の重篤な合併症です。
- 重篤な転帰を防ぐためには、迅速な認識と管理が不可欠です。
- リスク軽減のためには、医療提供者の認識が不可欠です。
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