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関連する概念動画

What is the Immune System?01:38

What is the Immune System?

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Overview
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Humoral Immune Responses01:36

Humoral Immune Responses

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Overview
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Active versus Passive Immunity01:31

Active versus Passive Immunity

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Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
10.8K
Introduction to Lymphatic and Immune System01:22

Introduction to Lymphatic and Immune System

17.6K
Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are...
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Functions of the Lymphatic and Immune System01:28

Functions of the Lymphatic and Immune System

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The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
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Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

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関連する実験動画

Updated: Feb 6, 2026

Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses
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Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses

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尿で免疫のトラブルを洗い流す

David S Schneider1

  • 1Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA.

Cell metabolism
|February 4, 2026
PubMed
まとめ

免疫応答の活性化は宿主に害を与える可能性があります。トロハらは、全身性炎症を持つマウスが尿中にサイトカインを排泄することでサイトカインによる損傷を軽減できることを実証しました。

背景:

  • 免疫応答は、病原体と戦うために不可欠ですが、逆説的に宿主に害を与える可能性があります。
  • 全身性炎症は、広範な炎症応答を伴い、宿主の損傷につながる可能性があります。
  • サイトカインは免疫応答における主要なシグナル分子ですが、過剰に循環すると有害になる可能性があります。

結論:

  • 全身性炎症中の自己誘発性損傷に対する重要な宿主防御メカニズムとしての尿中サイトカイン排泄。
  • この経路を理解することは、炎症性疾患の新しい治療戦略を提供する可能性があります。

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Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
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関連する実験動画

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Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network
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Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network

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Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
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