テストステロンとリスク回避に関連性なし:メタアナリシスによるレビュー
Irene Sánchez Rodríguez1, Luca Bailo1, Folco Panizza1
1Molecular Mind Lab, IMT School for Advanced Studies Lucca, Piazza San Francesco, 19, Lucca, 55100, Italy.
Neuroscience and biobehavioral reviews
|February 4, 2026
まとめ
テストステロンはリスク行動に信頼できる影響を与えない。包括的なメタアナリシスでは有意な関連性は見られず、リスク選好のホルモン的基盤という考えに疑問を投げかけている。
科学分野:
- 神経内分泌学、行動経済学、社会神経科学
背景:
- テストステロンとリスク行動の関係は、科学文献で一貫して報告されていません。既存の研究は複数の分野にまたがっており、方法論や結果が様々です。
研究 の 目的:
- テストステロンとリスク選好の関係を明確にする包括的なメタアナリシスを実施すること。多様な経験的研究からのデータを集計し、全体的な効果量を決定すること。
主な方法:
- 52の研究(N=17,340)の多層ランダム効果メタアナリシスを実施しました。テストステロンレベル/操作とリスク選好の相関を、様々な実験パラダイムで検討しました。出版バイアスをトリム&フィルおよびフェイルセーフN法を用いて評価しました。
主要な成果:
- 集計された効果量は統計的にゼロ(r = -0.0021)であり、テストステロンとリスク行動の間に信頼できる関連性がないことを示しています。異質性が観察され、宝くじベースのタスクのみがわずかな正の相関を示しました。テストステロンとリスクの相関において、性差は認められませんでした。
結論:
- これらの発見は、人間のリスク選好の一般的なホルモン的基盤という仮説に疑問を投げかけます。リスク行動は、タスクの具体性や文脈を含む生物心理社会モデルによって影響される可能性が高いです。将来の研究では、正確なメカニズムの洞察を得るために、事前登録されたマルチメジャーデザインと直接的な内分泌アッセイを使用する必要があります。
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