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人工内耳移植片受信者における蝸牛内電気蝸電図振幅パターンの縦断的解析
Marlies Geys1, Ahmet Kunut, Rahel Bertschinger
1Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Ear and hearing
|February 6, 2026
まとめ
人工内耳(CI)移植片受信者における術直後の電気蝸電図(ECochG)振幅の低下は、聴覚保持(HP)と関連しています。電極アレイ挿入中および挿入後にECochG振幅と位置をモニタリングすることで、聴覚成績に影響を与える蝸牛内の変化を明らかにすることができます。
科学分野:
- 耳介音響放射と電気生理学
- 聴覚神経生理学
- 人工内耳技術
背景:
- 蝸牛内電気蝸電図(ECochG)は、人工内耳(CI)移植片受信者における蝸牛機能をモニタリングする上で有望です。
- 電極アレイ(EA)挿入後のECochG振幅変動、聴覚機能配置位置、および聴覚保持(HP)との関係は、さらなる調査が必要です。
主な方法:
- 測定可能な残存聴覚を有する80人の成人CI移植片受信者を対象に、術中(EA挿入中および挿入直後)、および術後(7週および1年)の4つの時点でのECochG記録を実施しました。
- 測定では500 Hzのトーンバーストを使用し、交互極性応答間の差を分析しました。
- 聴覚機能配置位置はCTスキャンで決定し、聴覚保持はHEARRINGグループの式を用いて評価しました。
結論:
- ECochG振幅の術早期の低下は一般的であり、聴覚保持率の低下と相関しており、早期の蝸牛内反応を軽減するための戦略の必要性を示唆しています。
- ECochGは、時間経過に伴う蝸牛内プロセスをモニタリングする上で価値があり、術中の振幅と位置は安定したままでした。
- 非頂点ピークパターンは、挿入外傷ではなく、蝸牛の完全性の変動を示す可能性があります。
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