関連する実験動画
Updated: Jul 11, 2026

09:41
Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
Published on: June 17, 2014
まとめ
本研究は、以前に公開された記事DOIを訂正するものです。この訂正により、科学的誠実性のための正確な引用と参照が保証されます。
科学分野:
- 科学出版;学術コミュニケーション
背景:
- 科学文献における正確性は非常に重要です。;適切な引用は研究の完全性を保証します。
研究 の 目的:
- 公開された記事のデジタルオブジェクト識別子(DOI)のエラーを訂正すること。;科学データベースにおける正確な記録を維持すること。
主な方法:
- 誤ったDOIを特定すること。;正しいDOIを含む訂正通知を発行すること。
主要な成果:
- 記事のDOIは10.1016/j.igie.2023.07.002に更新されました。;公開された著作物への正確なリンクが保証されました。
結論:
- 正確なDOIは、科学記事の発見可能性と追跡可能性に不可欠です。;この訂正は、学術出版の基準を維持するものです。
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Proofreading
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Mismatch Repair
Overview
Proofreading
Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Proofreading
Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore, it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Mismatch Repair
Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
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The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
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