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関連する概念動画

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

10.6K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
10.6K
Preparation of Samples for Electron Microscopy01:20

Preparation of Samples for Electron Microscopy

7.2K
To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...
7.2K
Voltage01:13

Voltage

4.3K
The movement of electrons in a conductor requires some form of energy or work, usually provided by an external force, like a battery. This force is called the electromotive force or voltage. The voltage between two points, referred to as points "a" and "b," in an electric circuit is the energy (or work) needed to move a unit charge from point "a" to point "b," and this relationship is expressed mathematically as
4.3K
Multiple Voltage Sources01:25

Multiple Voltage Sources

1.8K
Generally, a single battery is not enough to power some devices. In such cases, batteries can be combined in two ways: in series or in parallel.
In series, the positive terminal of one battery is connected to the negative terminal of another battery. Hence, the voltage of each battery is added to give the net voltage, which is increased because each battery boosts the electrons that enter it. The same current flows through each battery because they are connected in series.
Batteries are...
1.8K
Voltage Dividers01:14

Voltage Dividers

1.4K
In electrical circuits, resistors can be connected in series, sequentially linked one after the other. In a series configuration, the same current flows through each resistor. Ohm's law is a fundamental principle to understand the behavior of resistors in series. It expresses the voltage across these resistors in terms of the current and resistance.
Kirchhoff's voltage law implies that the sum of the voltages across the resistors in series equals the source voltage. This means that the current...
1.4K
Three-Phase Voltages01:30

Three-Phase Voltages

592
A three-phase generator produces three voltages that are equal in magnitude but have a phase difference of 120 degrees. This identical magnitude and equal phase separated voltages are known as the balanced voltages and help to minimize power loss while ensuring a steady delivery of energy to connected loads. As voltage sources in a three-phase system can be configured in a wye or a delta formation, the loads connected to these systems can also be arranged in either configuration. This...
592

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関連する実験動画

Updated: Feb 7, 2026

Sample Preparation and Imaging of Exosomes by Transmission Electron Microscopy
11:15

Sample Preparation and Imaging of Exosomes by Transmission Electron Microscopy

Published on: January 4, 2018

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電圧イメージング顕微鏡における時間サンプリングの意義

Jakub Czuchnowski, Jerome Mertz

    ArXiv
    |February 6, 2026
    PubMed
    まとめ

    電圧イメージング顕微鏡は異なるサンプリング方法を使用します。走査型顕微鏡は低信号対雑音比に優れ、広視野型顕微鏡は標本化不足のデータに適しており、最適なパラメータ選択を導きます。

    科学分野:

    • 神経科学
    • 光学イメージング
    • 生物物理学

    背景:

    • 電圧イメージング顕微鏡は、ニューロン活動の研究に不可欠です。
    • 走査型および広視野型を含む、さまざまな顕微鏡技術が存在します。
    • 信号忠実度に対する時間サンプリングの影響は、十分に調査されていません。

    研究 の 目的:

    • 走査型および広視野型顕微鏡の時間サンプリングを分析します。
    • サンプリングが電圧スパイク検出忠実度に与える影響を評価します。
    • 電圧イメージングパラメータの最適化のためのガイダンスを提供します。

    主な方法:

    • 数学的フレームワークを開発しました。
    • 解析モデリングとモンテカルロシミュレーションを利用しました。
    • さまざまな条件下でのパフォーマンスを比較しました。

    主要な成果:

    • 走査型顕微鏡は、低い信号対雑音比およびスパースなスパイクの検出において優れています。 広視野型顕微鏡は、時間的アンダーサンプリングおよび高いスパイク検出率でより良好に機能します。 フレームレートがインジケータの減衰に一致すると、パフォーマンスは収束します。

    結論:

    キーワード:
    電圧イメージング顕微鏡時間サンプリングニューロン活動走査型顕微鏡広視野型顕微鏡信号対雑音比スパイク検出

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    Cortical Actin Flow in T Cells Quantified by Spatio-temporal Image Correlation Spectroscopy of Structured Illumination Microscopy Data
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    Miniaturized Sample Preparation for Transmission Electron Microscopy
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    Miniaturized Sample Preparation for Transmission Electron Microscopy

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    関連する実験動画

    Last Updated: Feb 7, 2026

    Sample Preparation and Imaging of Exosomes by Transmission Electron Microscopy
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    Cortical Actin Flow in T Cells Quantified by Spatio-temporal Image Correlation Spectroscopy of Structured Illumination Microscopy Data
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    Cortical Actin Flow in T Cells Quantified by Spatio-temporal Image Correlation Spectroscopy of Structured Illumination Microscopy Data

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    Miniaturized Sample Preparation for Transmission Electron Microscopy
    09:04

    Miniaturized Sample Preparation for Transmission Electron Microscopy

    Published on: July 27, 2018

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    • 電圧イメージングにおける最適な時間サンプリングの選択のためのガイダンスを提供します。
    • フレームレート500 Hz未満での走査型電圧イメージングの使用は推奨されません。