オンコセルカ症の伝播地帯の定義：運営上の洞察とゲノムおよび生態学的進歩の統合

Onchocerciasis is a parasitic infection caused by the filarial nematode Onchocerca volvulus and transmitted through the bites of blackflies of the genus Simulium that breed in rivers and streams. The current World Health Organisation (WHO) definition of transmission zones is limited, leaving country programmes to address challenges such as delineating transmission zones correctly, addressing blackfly migration, managing parasite and host movement, and handling cross-border transmission issues. A more data-driven approach to the practical definition of transmission zones in African countries would be advantageous. A review of the documents in the WHO Institutional Repository for Information Sharing (WHO IRIS) and using standard search engines (e.g. PUBMED, Google Scholar), has identified previously less-recognised factors that could enhance the definition and use of transmission areas in onchocerciasis areas. These guiding observations integrate historical operational, entomological, epidemiological, and ecological information with genomic aspects.