感染したプラスチック胆道ステントのFDG PET/CTによる同定:症例報告
Yeon-Hee Han1, Seong-Hun Kim2, Chang-Seop Lee2
1Department of Nuclear Medicine, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Cyclotron Research Center, Molecular Imaging and Therapeutic Medicine Research Center, Jeonbuk National University Medical School and Hospital, Jeonju, Jeonbuk, Republic of Korea.
Medicine
|February 6, 2026
まとめ
F-18フルオロデオキシグルコース陽電子放出断層撮影/コンピュータ断層撮影(FDG PET/CT)は、再発熱患者における感染性胆道ステントを効果的に特定しました。迅速なステント除去と標的抗生物質療法により敗血症は解消され、FDG PET/CTの有効性が強調されました。
科学分野:
- 核医学;放射線学;感染症
背景:
- 原因不明の発熱の診断上の課題、特に従来の画像検査で結論が得られない場合。
- 留置された胆道ステントは、持続性敗血症の原因となり得る。
- 不明瞭な感染の検出におけるF-18フルオロデオキシグルコース陽電子放出断層撮影/コンピュータ断層撮影(FDG PET/CT)の役割。
研究 の 目的:
- FDG PET/CTの感染性胆道ステント検出における診断的有用性を例示すること。
- 胆道介入後の再発性敗血症管理におけるFDG PET/CTの有効性を示すこと。
主な方法:
- 胆道ステントの既往歴があり、再発熱を呈した82歳女性の症例提示。
- 診断ワークアップにはFDG PET/CT、内視鏡検査、微生物培養が含まれた。
- 処置には内視鏡的ステント除去と標的抗生物質療法が含まれた。
主要な成果:
- FDG PET/CTは胆道ステント先端の限局性高集積を示し、感染を示唆した。内視鏡検査により、十二指腸乳頭炎、バイオフィルム形成、ステント部位のスラッジが確認された。微生物培養により、大腸菌と肺炎桿菌が同定された。
結論:
- FDG PET/CTは、原因不明の再発熱患者における感染性胆道ステントの診断に有用なツールである。
- FDG PET/CTの早期利用は、不要な処置を防ぎ、タイムリーで標的を絞った介入を促進することができる。
- 治療の成功には、ステント除去と培養指示による抗菌療法が含まれ、症状の改善につながった。
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