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Cognitive Dissonance01:38

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Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
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Elements and Compounds01:27

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Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond.
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Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
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The periodic table arranges atoms based on increasing atomic number so that elements with the same chemical properties recur periodically. When their electron configurations are added to the table, a periodic recurrence of similar electron configurations in the outer shells of these elements is observed. Because they are in the outer shells of an atom, valence electrons play the most important role in chemical reactions. The outer electrons have the highest energy of the electrons in an atom...
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Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond. Elements are classified as atomic or molecular based on the nature of their basic units.
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Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
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A chemical symbol is an abbreviation used to indicate an element or an atom of an element. For example, the symbol for mercury is Hg. The same symbol is used to indicate one atom of mercury (microscopic domain) or to label a container of many atoms of the element mercury (macroscopic domain).
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Updated: Feb 8, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
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循環性微量元素と認知機能障害との関連

Masroor Anwar1, Javed A Qadri2, Mohd Suhail Ashar1

  • 1Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
|February 6, 2026
PubMed
まとめ

環境汚染により、インドの認知機能障害(CI)患者における微量元素レベルが上昇した。リチウム(Li)およびアルミニウム(Al)を含む8つの元素がCI患者で有意に高値を示し、神経毒性との関連および早期疾患検出の可能性を示唆している。

キーワード:
アルツハイマー病微量元素認知機能障害ICP-MS神経変性神経毒性

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科学分野:

  • 環境科学と毒性学
  • 神経科学と神経学
  • 分析化学

背景:

  • インドにおける急速な工業化と都市化は、微量元素の環境汚染を増加させている。
  • 血液中の微量元素濃度の不均衡は、ホメオスタシスを破壊し、神経変性効果を引き起こす可能性がある。
  • 微量元素と認知機能低下との関連に関するデータは限られている。

主な方法:

  • 誘導結合プラズマ質量分析法(ICP-MS)を用いて65人の参加者の19の元素を定量化した。
  • 認知能力を評価するために包括的な臨床的および機能的評価を実施した。
  • CI患者群と対照群の間で微量元素レベルを比較した。

結論:

  • 調査した微量元素(Li、Al、V、Mn、Co、Ni、Zn、Ag)は、CI患者において特徴的なシグネチャを形成する可能性がある。
  • 高齢者におけるこれらの微量元素シグネチャの検出は、元素誘発性神経毒性の早期管理に役立つ可能性がある。
  • この研究は、認知機能低下の早期特定と介入のための潜在的なバイオマーカーを強調するものである。