脳卒中生存者における実行機能障害と軽度から重度の上肢障害との関連：安静時機能的近赤外分光法研究

We aimed to observe the association between executive function and mild to severe upper extremity deficits in stroke survivors. Meanwhile, applying functional Near-Infrared Spectroscopy (fNIRS) to investigate the resting-state functional connectivity (FC) patterns of patients with post-stroke executive impairment (PSEI).

122 stroke survivors with mild to severe upper extremity deficits were enrolled. The Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery (FAB), and Stroop color-word test assessed cognitive and executive function. The Fugl-Meyer assessment of the upper extremity (FMA-UE) and Action Research Arm Test (ARAT) assessed motor function. They were collected fNIRS data at the resting state. RESULTS：: CONCLUSION: Our study suggests that the association between executive function and upper extremity after stroke is associated with the degree of upper extremity deficits. Additionally, the FC among cortical and subcortical brain regions were different with varying degrees of upper extremity deficits in PSEI patients.